Stem Cell and Cancer Research


Nasional Research

Tumor necrosis factor-α-activated mesenchymal stem cells accelerate wound healing through vascular endothelial growth factor regulation in rats

See original article in: https://www.univmed.org/ejurnal/index.php/medicina/article/download/635/524 ABSTRACT BACKGROUND Wounds are areas of physical or thermal damage of the epithelial layer of skin or mucosa. The wound healing process consists of hemostasis, inflammation, proliferation, and remodeling. Mesenchymal stem cells (MSCs) play a role in wound healing by suppressing potent proinflammatory molecules, such…

TNF-α-Activated MSC-CM Topical Gel Effective in Increasing PDGF LEVEL, Fibroblast Density, and Wound Healing Process Compared to Subcutaneous Injection Combination

Abstract Mesenchymal stem cells (MSCs) are multipotent stromal cells that have the capacity to regenerate tissue damage. However, they have several limitations. MSC-CM as a new approach treatment is widely used to solve the limitation of MSC in wound healing. The aim of this study was to evaluate the effectiveness…

The Role of Mesenchymal Stem Cells on Regulating PDGF and Islet Cells in Diabetes

See original article in Brawijaya University : https://jkb.ub.ac.id/index.php/jkb/article/download/2274/658 ABSTRACK Diabetes is a group of metabolic disease characterized by increased level of blood glucose as a result of defect in β Cells destruction and or insulin resistance. Clinical studies showed that transplantation of islet is sufficient cure to relief from the…
Effect-of-TNF-α-Serial-Doses-Inducition-on-Increasing-VEGF-dan-PDGF-in-Mesenchymal-Stem-Cells

Effect of TNF-α Serial Doses Inducition on Increasing VEGF dan PDGF in Mesenchymal Stem Cells

See original articles in Unpad: http://journal.fk.unpad.ac.id/index.php/mkb/article/download/1278/pdf Abstract Mesenchymal Stem Cells (MSCs) have immunoregulation and regeneration capabilities through suppression of proinflammatory mediator release and increase of proliferative molecules, particularly the vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) TNF-α activated MSC in a certain dose has the ability to…